Nosocomial Asthma

The pathophysiological mechanisms of asthma include bronchoconstriction and obstruction of the airways. This is due to the effect of the edema that occurs in the airways as a result of a series of cellular inflammatory reactions.The cells that are involved are the lymphocytes, mast cells,eosinophils, neutrophils, macrophages, resident cells and epithelial cells together with other inflammatory mediators recruited by the body in response to foreign antigen but unfortunately turns into an overly cellular response.

In asthmatic condition, a phenomenon in arterial blood gas pattern is observed, where variations in blood arterial carbon dioxide concentration: PaCO2 and the changes in blood Ph levels are used as an indication of the severity of the asthmatic condition. This is the increase in the PaCO2 and the drop in the Ph levels during an asthma attack. At a certain degree where the lungs cannot exhale any more carbon dioxide from the lungs due to airway obstruction, there is an increase in PaCO2 in the blood and consequently a drop in the blood Ph levels below the standard levels of 7.4, as the asthmatic condition worsens.

Among the factors contributing to both acute and chronic asthma includes, environmental factors such as environmental exposure to allergens and smoke, also areas prone to respiratory infections are contributing factor.Allergens are known to trigger body’s immunity thus bringing about a deployment of the cellular immune mechanism.

First Aid Tips For an Asthmatic patient.

The first indication of an asthmatic attack is commonly a shortness of breath which is mostly characterized by a struggling wheezing breath. The patient may later become immobilized, and they convulse if the situation is not handled the patient dies. Once it has been identified that a person is having an asthmatic attack follow the following tips.

  • Sit them up and allow them to bend forward a bit to create more lung space for smooth breathing.
  • Eliminate the allergen or take the person away from the triggering cause, this may be away from the dusty or smoky or cold places.
  • Help the patient take their antiasthmatic medication such as using the inhaler or taking antihistamine drugs.
  • Call for medical help if the patient does not show any improvement.